Based on the laboratory test results, the Basic package estimates the risk of having the following 7 disease groups.
Based on the laboratory test results, the Normal package estimates the risk of having the following 12 disease group.
Based on the laboratory test results, the Premium package estimates the risk of the following 14 disease groups.
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Thyroid diseases include a wide variety of disorders affecting the thyroid gland, including congenital (familial) defects, iodine deficiency conditions, hypo and hyperthyroidism, thyrotoxicosis, thyroiditis and other thyroid disorders. In case of involvement, consultation with an endocrinologist and further specific thyroid testing is recommended
The main appearance of diabetes includes insulin-dependent and non-insulin-dependent manifestations, acquired nutritional (e.g. malnutrition) and genetic origins. As diabetes is one of the most complex chronic diseases, a complex specialist investigation (internal medicine, diabetology) is required to accurately identify the causes and associated diseases.
Acute and chronic diseases of the liver including fibrosis, inflammation, shrinkage, toxic, hereditary, infectious and other causes, excluding cancer. In case of involvement, a visit to an internist or a gastroenterologist/hepatologist, a detailed specialist examination and a panel test with specific liver parameters are recommended.
Any non-infectious inflammation of the colon and small intestine, such as Crohn's disease, ulcerative colitis, coeliac disease (celiac disease) or an absorption disorder associated with food intolerance. In the case of susceptibility, detailed panel tests (e.g. screening for celiac disease), food allergy tests and consultation with a specialist in internal medicine, gastroenterology or proctology may be recommended to rule out these diseases in a targeted way.
This group includes all vitamin, mineral, metal and trace element-related nutritional deficiencies and anaemia but also includes protein deficiency disorders. The algorithm estimates the presence of anaemia from the blood count and considers all unilateral or inadequate blood count abnormalities associated with nutritional deficiencies as affected. In the case of involvement, it is recommended to consult an internist, haematologist, or dietician and to perform a detailed vitamin/nutrient panel to rule out the disease or to identify the exact cause.
All anaemia of non-nutritional origin (or not directly related to nutrition), including anaemia caused by enzyme defects, inherited or acquired haematological disorders other than cancer (e.g. thalassaemia, sickle cell disorders, haemolytic anaemia, aplastic and other anaemia pathologies). In case of involvement, consultation with a specialist in internal medicine or haematology and a specific and detailed blood panel to rule out the disease or to identify the exact cause is recommended.
Immunodeficiencies include hereditary and acquired partial, mixed and complex immune deficiencies, some autoimmune diseases (e.g. sarcoidosis) and other non-cancer (auto)immune diseases. In case of involvement, a detailed immune panel is recommended and consultation with a specialist immunologist to exclude and identify the causes.
Systemic autoimmune diseases that affect the whole body or several physiological functions, such as various forms of rheumatoid arthritis, complex connective tissue systemic diseases (SLE, systemic sclerosis or other connective tissue systemic involvement - e.g. Sjögren's syndrome) or systemic myopathies. Most of these are difficult to diagnose, and in case of suspicion of involvement (if suggested by previous complaints or medical history) it is recommended to consult an immunologist / internist / endocrinologist and to perform specific tests to confirm/reject the suspicion.
Abnormalities in lipid metabolism, which may be either a consequence of other chronic diseases or a precursor to other more serious conditions. This includes hereditary and acquired hyperlipidaemias. If affected, it may be worthwhile to have a detailed lipoprotein profile and consult a lipidologist (internist) and investigate the underlying causes.
These include diseases of the bile (e.g. gallstones/ gallbladder inflammation) and (acute) inflammatory and other gastrointestinal diseases of the pancreas. In case of involvement, it is recommended to consult an internist (gastroenterologist) and possibly undergo further (specific) panel testing
Inflammatory and other diseases of the kidney, including inflammation of the glomerular, tubular and interstitial tissues, and any other disease associated with renal dysfunction and/or loss of function, including both acute and chronic severe renal failure. In case of suspicion, a detailed renal profile and consultation with a nephrologist (internist) is recommended.
Pathologies that adversely affect the functioning of the circulatory system, which can be serious in themselves or are often precursors to serious/life-threatening functional disorders. These include ischaemic heart disease (disturbances in the blood supply to the heart), valvular heart disease (aortic and myocardial disease), cerebrovascular disease (cerebrovascular disease), atherosclerosis and thrombotic conditions. In case of involvement, it is recommended to consult an internist/cardiologist and, if necessary, to undergo further (imaging) diagnostic tests.
Chronic malignant diseases, which include the major neoplasms of the haematopoietic system (leukaemias and lymphomas), the most common adenocarcinomas (gastrointestinal cancers, breast cancer, prostate cancer), the most common squamous cell tumours (gynaecological tumours, respiratory tract tumours), as well as mixed and specialised tumours (e.g. melanomas) and endocrine gland tumours (e.g. thyroid), excluding tumours of primary nervous system origin. Importantly, the majority of cancers are not diagnosed by blood sampling (except for tumours of the haematopoietic system), so in many cases mathematical models only estimate risk by looking for secondary patterns and the quantified results are much less reliable than for other disease groups. If your result shows any risk, your medical history will always be reviewed by a qualified oncologist/haematologist/ internist (who will also contact you if necessary to learn more about your health and medical history) and decide whether further investigations are necessary.
Rare conditions affecting less than one in 2,000 people (most of them less than one in ten thousand). Special mathematical algorithms search for abnormalities in laboratory findings that affect a negligible percentage of (mainly adult) patients and may be the result of hidden, difficult-to-detect pathological lesions. The algorithms are able to estimate the risk of rare metabolic diseases (e.g. familial hypercholesterolaemia, familial chilomicronaemia syndrome, Gaucher or Wilson's disease, haemochromatosis), rare haematological disorders (e.g. porphyria, haemophilia, cryoglobulinemia), rare autoimmune diseases (e.g. Behcet's disease, Still's disease), rare diseases affecting the endocrine glands (e.g. Cushing's syndrome) and certain mitochondrial diseases (e.g. carnitine deficiency syndromes). If you are found to be affected, you still have a very low risk of the disease, but the increase in risk can be very high (for example, even if you have a 100-fold increase in risk, your chances of being affected are less than 1 in 100 in 1 in 15,000 people, but this increase in risk is significant enough for a specialist to treat your case). Therefore, if you are at risk of any rare disease, your medical history will be reviewed by a rare disease specialist in internal medicine/haematology/immunology, if necessary by face-to-face or telephone consultation and by asking about your medical history and any symptoms.
